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Williford is a small incorporated town in eastern Sharp County, Arkansas, near the Spring River, one of the state's most popular streams for recreational floating.

The town is named for Ambrose Williford, a prominent early landowner; the first white settler in the area, Jeremiah Pitt Baird, established his homestead on the banks of the Spring River in 1841.

The railroad reached Williford in 1883 — the first train passed through on October 1, 1883, drawing spectators from miles around — and the line, later part of the Frisco Railroad, made the town a center of shipping and commerce.

A limestone quarry opened east of town in 1884 shipped forty to fifty railroad cars of stone per day at its height, and its company housing camp, where all fourteen houses were painted green, was known as Greenville.

By 1890 Williford had three general stores, a saloon, a cotton gin, a blacksmith shop, a one-room schoolhouse, a doctor's office, and a post office, and a ten-room hotel opened in 1912.

Williford was officially incorporated on December 8, 1914, when it ranked among Sharp County's largest and fastest-growing towns.

The 1920 census counted 357 people in Williford, its recorded peak, but a major fire in 1929, recurring Spring River floods, and the decline of rail passenger service shrank the town steadily afterward.

The 2020 census counted 79 residents in Williford, in a town covering about 0.35 square miles.

At the 2000 census, Williford's 63 residents lived in just 32 households.

Williford's Methodist church, built in 1910, was listed on the National Register of Historic Places in 1992, though only the town's Church of Christ, established in 1912, still holds services.