Biohazard and Pathogen Disinfection in Wynne, AR

Wynne is the largest city in Cross County, Arkansas, and its county seat, sitting in south-central Cross County where the fertile Arkansas Delta meets the western slope of Crowley's Ridge, with the L'Anguille River west of town.

Wynne began in 1882 as the St. Louis, Iron Mountain and Southern Railroad was being built through the area, when a derailed train left behind a boxcar that was set upright, used as a building, and christened Wynne Station.

The town was named for Captain Jesse Watkins Wynne, a Forrest City banker who became the first president of the Bank of Eastern Arkansas, and the Wynne Station post office opened on September 27, 1882.

Wynne was incorporated in May 1888, and after the east-west rail line crossed the north-south line at what became known as Wynne Junction, the town outgrew the older county seat of Vanndale and became the Cross County seat in 1903.

U.S. Route 64 and Arkansas Highway 1 later made Wynne an important highway crossroads for several decades in addition to a railroad town, until Interstate 40 drew long-distance traffic away.

The 2020 census counted 8,314 people in Wynne living in 3,329 households, with 3,702 housing units in the city.

Wynne is the closest city to Village Creek State Park, the second-largest state park in Arkansas.

The Wynne School District operates Wynne Primary School, Wynne Intermediate School, Wynne Junior High School, and Wynne High School, and the city also hosts a branch of East Arkansas Community College on Falls Boulevard.

On March 31, 2023, an intense EF3 tornado with winds reaching 150 miles per hour tore through Wynne, killing four people, injuring 26, and heavily damaging Wynne High School.

Ten sites in Wynne are listed on the National Register of Historic Places, including the Wynne Wholesale Commercial Historic District and the East Hamilton Avenue Historic District.