Crime Scene and Trauma Cleanup in Mayersville, MS

Mayersville is a town on the east bank of the Mississippi River and the county seat of Issaquena County, Mississippi.

The 2020 census counted 433 residents in Mayersville, with 155 households, down from 547 in 2010 and 795 in 2000.

The town covers 1.10 square miles, all land, at an elevation of 102 feet, and is separated from the river by a levee.

Non-Native settlement began in 1830, when Ambrose Gipson bought land along the river and founded "Gipson's Landing," a cotton-shipping port for Issaquena and Sharkey counties.

David Mayer purchased Gipson's Landing in 1870, the town of Mayersville was founded in 1871, and the legislature established it as the Issaquena County seat in 1872.

The town's port declined as railways spread across the South, though no railway was ever built to Mayersville, and a levee built after the hugely destructive flood of 1927 cut off its direct river access.

The Mayersville Archeological Site, added to the National Register of Historic Places in 1980, holds earthwork mounds built mainly in the Mayersville phase (AD 1200-1400) of the earlier Mississippian culture.

The current Issaquena County courthouse in Mayersville was built in 1958.

In 1976, civil rights activist Unita Blackwell was elected mayor of Mayersville, the first female African-American mayor in Mississippi, and she served until 2001.

Mississippi Highway 1 passes through town, leading north 39 miles to Greenville and south 22 miles to U.S. Route 61 at Onward, while Mississippi Highway 14 has its western terminus in Mayersville.