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Scottsbluff is a city in Scotts Bluff County and the largest city in the Nebraska Panhandle, with 14,436 residents in the 2020 census.

Scottsbluff was founded in 1899 by the Lincoln Land Company, a subsidiary of the Burlington Railroad, on the north bank of the North Platte River.

When Burlington tracks reached the town in 1900, a discarded boxcar served as the first depot, and Scottsbluff — the first town in the region located on a rail line — drew older businesses away from Gering across the river.

The city is named for Scotts Bluff, the towering landmark across the North Platte River now protected by the National Park Service as Scotts Bluff National Monument; the bluff itself was named for Hiram Scott, a Rocky Mountain Fur Company fur trader found dead nearby after a fur expedition.

Scottsbluff and Gering, founded in 1887 at the base of the bluff, have grown together into one micropolitan area — though the county seat of Scotts Bluff County is Gering, not Scottsbluff.

The 2020 census counted 14,436 people in 5,917 households in Scottsbluff, and Hispanic or Latino residents made up about 31.7 percent of the population.

Scottsbluff is home to the main campus of Western Nebraska Community College, and the University of Nebraska–Lincoln operates its Panhandle Research and Extension Center in the city.

At an elevation of about 3,888 feet, Scottsbluff keeps Mountain Time — an hour behind most of Nebraska — and has a cold semi-arid climate of hot summers, dry cold winters, and chinook winds that can abruptly break winter cold spells.

Local points of interest include the Riverside Discovery Center zoo, nearby Lake Minatare State Recreation Area, and the grave of Mormon pioneer Rebecca Winters along the old emigrant-trail corridor.

Scottsbluff's population peaked at 15,039 in the 2010 census before easing to 14,436 in 2020.