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Talmo is a small incorporated town in Jackson County in northeast Georgia, a county whose seat is Jefferson.

The community was settled around 1840 along an old Cherokee trail, when the area was still little more than wilderness with only a few houses.

Talmo's name is derived from the Creek Indian word Talomeco, meaning "home of the Chief Tallassee," and the town proudly calls itself "The Jewel of Jackson County."

Talmo began to grow in the early 1900s when the Gainesville Midland Railroad put in a side track; local residents built the depot at their own expense and labor, and the railroad made Talmo a regular stop.

The Georgia General Assembly incorporated Talmo as a town on August 9, 1920.

The 2020 census counted 257 people in Talmo, up from 180 residents in 2010.

The town's population has swung sharply over the decades — the 2000 census counted 477 people in 146 households, a figure that reflects changing town boundaries as much as growth.

Talmo's former city hall was located in a general store dating back to the town's earliest years, a building that has been placed on the National Register of Historic Places.

The town's newer City Hall also houses the City Library, and Talmo's first bed and breakfast, Mt. Creek Manor, opened in 2011.