Biohazard Cleanup Near West Adrian Adrian, TX

Adrian is a small city in south-central Oldham County in the Texas Panhandle, about 47 miles west of Amarillo.

Adrian is famous as the geo-mathematical midpoint of historic U.S. Route 66 — it sits exactly 1,139 miles from both Chicago, Illinois, and Los Angeles, California, a fact proudly painted on town signage.

Adrian began in 1900 as a station on the Rock Island Railroad, and the town was formally established in the summer of 1909 after the Chicago, Rock Island and Gulf Railway was completed through the area.

Despite its early start, Adrian was not incorporated until 1953.

Adrian's best-known landmark is the Midpoint Café, built in 1928 — its longtime owner Fran Houser was the inspiration for Flo, the owner of Flo's V-8 Café in Pixar's animated film Cars.

Historic Route 66 through Adrian has been bypassed by Interstate 40, which crosses the city today along with Texas State Highway 214.

Adrian had a population of 128 at the 2020 census, down from 166 at the 2010 census.

The 2020 census counted just 48 households and 36 families in the entire city of Adrian.

Local students attend the Adrian Independent School District's single K-12 campus, Adrian School, home of the Matadors, who compete in UIL Class 1A athletics.

Adrian is one of only two incorporated cities in Oldham County, a vast Panhandle ranching county that had just 1,758 residents in total at the 2020 census.