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Mathis is a city in San Patricio County on Interstate 37, northwest of Corpus Christi, and is part of the Corpus Christi metropolitan area.

Mathis was founded in 1887, when Thomas H. Mathis received the naming rights after donating 300 acres for a townsite and school as the San Antonio and Aransas Pass Railroad laid tracks across San Patricio County.

Thomas H. Mathis and his brother J. M. Mathis held about 37,000 acres of land in the vicinity of the new town.

Mathis did not incorporate until 1939, more than fifty years after it was founded.

In the 1930s the Nueces River was dammed to form Lake Mathis — since renamed Lake Corpus Christi — a roughly 21,000-acre reservoir lying about four miles southwest of Mathis.

Construction of the Wesley Seale Dam in the late 1950s raised the level of Lake Corpus Christi and made the Mathis area desirable for weekend homes.

Mathis serves as a major gateway to Lake Corpus Christi and the state park on its shores.

Mathis had 4,333 residents at the 2020 census, down from a peak population of about 5,910 in 1988.

Nearly 90% of Mathis residents identified as Hispanic or Latino in the 2020 census.

Recent Census Bureau estimates count about 1,800 households in Mathis, with roughly 64% of its housing owner-occupied.