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Greenville is a village in Outagamie County, Wisconsin, just west of the city of Appleton, and one of the 18 communities that make up the Fox Cities, the third-largest metropolitan area in Wisconsin.

Greenville was founded in 1848 as Greenville Station and changed its name to Becker in 1879, after its first postmaster, Anton Becher, before changing its name back to Greenville in 1896.

Greenville spent most of its history as a town and only became a village in 2021, when its eastern half incorporated in January and successfully annexed the remaining western half of the old township that June.

Greenville's unusual two-step incorporation made it one of the largest villages in the state of Wisconsin by both area and population.

Greenville covers about 35.8 square miles in south-central Outagamie County.

Greenville counted 12,687 residents in the 2020 census, and Census Bureau figures for 2020–2024 put it at about 4,727 households with an owner-occupied housing rate of about 91%.

Greenville has been one of the Fox Cities' fastest-growing communities, growing from 6,844 residents in 2000 to 10,309 in 2010 and 12,687 in 2020.

Greenville is home to Appleton International Airport, located in the village's southeast corner, which serves as a major economic engine for the community.